Does PetLabCo.® ProBright® Advanced Work? My Vet-Reviewed Verdict

Written by Carol Bryant – Immediate Past President of the Dog Writers Association of America. 15+ years writing pet health content for outlets including CNN, Yahoo, and Dogster. Editor of Fidoseofreality.com. PetLabCo.® Consultant.

Reviewed by:  PetLabCo.® Consultant vet Dr Legend Thurman DVM, MSL, CVBP, MRCVS.

Additional expert perspective from Dr. Sharon Daley, DVM.

Editorial process: All product reviews at PetLabCo.® Learn are based on clinical evidence, verified customer feedback, expert veterinary consultation, and hands-on evaluation. Reviews are updated as new evidence emerges.

My verdict: Yes, PetLabCo.® ProBright® Advanced works well as a supportive addition to your dog’s dental routine – backed by two clinical studies, verified customer feedback from PetLabCo.® subscribers, and formulation guidance from a Board-Certified Veterinary Dentist.

A 28-day clinical study found ProBright® Advanced significantly reduced hydrogen sulfide, one of the most common compounds that produces bad breath, by 40% in a dog’s mouth.† A separate 90-day study revealed a 25% decrease in plaque formation, according to Dr. Jan Bellows, Board-Certified Veterinary Dentist.‡ ProBright® Advanced works best for dogs with mild tartar whose owners struggle with daily brushing.

This review is based on those two clinical studies, verified customer feedback from PetLabCo.® subscribers, and expert veterinary consultation.

My Editorial Rating

My rating is based on clinical evidence, ingredient quality, ease of use, and value against comparable dog dental powders on the market.

Category	Rating	Rationale
Effectiveness	4.5/5	Two clinical studies show measurable outcomes: 40% reduction in a common bad-breath compound in 28 days†; 25% reduction in plaque accumulation in 90 days‡
Ingredient quality	4.5/5	Patent-pending probiotic blend (Pediococcus pentosaceus, Lactiplantibacillus plantarum); NASC-certified; formulated with a Board-Certified Veterinary Dentist
Ease of use	5/5	Sprinkle-on-food format; no brushing required; four sizes tailored to dog weight
Value	4/5	Priced at $28.95/month (subscription, XS); competitive vs comparable clinically-tested dental powders
Overall	4.5/5	Best for dogs with mild tartar whose owners struggle with daily brushing

† A 28-day clinical study found ProBright® Advanced significantly reduced hydrogen sulfide, one of the most common compounds that produces bad breath, by 40% in a dog’s mouth.

‡ In a 90-day clinical study, dogs taking ProBright® Advanced daily had a plaque index score that was 25% lower than the control group. Statement attributed to Dr. Jan Bellows, Board-Certified Veterinary Dentist and PetLabCo.® Consultant.

Individual results may vary.

Key Takeaways: Does PetLabCo.® ProBright® Advanced Formula Work Well As A Dental Hygiene Support?

• PetLabCo.® ProBright® Advanced is a daily dental powder supplement formulated to help target tartar build-up and support fresher breath when used consistently.
• 90% of surveyed PetLabCo.® subscribers report seeing results with ProBright® Advanced.*
• It works well as support for oral cleanliness when used as directed, especially in hard-to-reach areas that toothbrushing alone may miss.
• Best results are seen when used alongside regular tooth brushing and routine veterinary care.
• Consistency is key – daily use may help maintain ongoing oral hygiene support.

*Based on a survey of PetLabCo.® subscribers who reported using ProBright® Advanced daily or almost daily for 90+ days. Results reflect customer feedback collected in September 2025 (n=456). Individual results may vary.

With thousands of dental products for dogs available, it’s understandable if you’re wondering ‘does PetLabCo.® ProBright® Advanced work?’ and feeling overwhelmed trying to choose between the options. When used consistently, as part of a complete daily dental/oral care routine, ProBright® Advanced can work well as a supportive addition to your dog’s wellbeing plan.

– Carol Bryant, PetLabCo.® Consultant

Introduction to PetLabCo.® ProBright® Advanced and How It Works

Are you considering adding PetLabCo.®’s ProBright® Advanced to your dog’s dental care routine? Maybe you’ve noticed tartar build-up or a sharper smell to your dog’s breath recently – this is pretty common. In fact, one of the top 10 reasons pet parents visit the veterinarian every year is for canine dental care.

Because tartar can form rapidly, often within 48 hours of eating, keeping your dog’s teeth clean and breath fresh requires regular tooth brushing and a consistent dental care routine.

Daily care is essential for maintaining your dog’s dental health. Many owners find it difficult to get their dog’s teeth brushed every day, which is why dental powder supplements are popular for supporting cleaner teeth and fresher breath.

This article will explain what PetLabCo.® ProBright® Advanced powder for dogs is, how to decide if it’s suitable for your pup, and whether you should add it to your dog’s daily dental care routine.  Looking to purchase this product? See the PetLabCo.® ProBright® Advanced product page.

How Dental Powder Supplements Work

Canine dental powder has quickly become a go-to solution for pet parents looking to provide further support for their dog’s oral health alongside toothbrushing. Designed to be a low-stress daily supplement, dog dental powder offers a simple way to help promote whiter teeth and fresher breath.

By administering the supplement once a day, using the provided scoop to add it to your dog’s meal, you can help maintain cleaner teeth and a healthier mouth, especially in those hard-to-reach areas that toothbrushing may struggle to reach. 

What Is PetLabCo.® ProBright® Advanced Formula, and What Does It Aim To Support?

ProBright® Advanced by PetLabCo.® is a dental powder supplement for dogs that can be easily given using the provided scoop. Each scoop contains a unique blend of patent-pending probiotics, brown algae, and other beneficial ingredients that help target tartar build-up, especially in hard-to-reach places that dog toothbrushes may struggle to reach.   

According to  Sharon Daley, DVM, Certified Veterinary Acupuncturist of Wake Forest, North Carolina, products like PetLabCo.® ProBright® Advanced can be a beneficial addition to a dog’s dental care routine.  

I love products that pet parents can use at home, especially those manufactured in the USA using premium-quality domestic and globally sourced ingredients. I have 11 dogs and cats, so I understand the importance of being practical about proactive care.

– Dr Sharon Daley, DVM, PetLabCo.® Consultant

So exactly what are the potential benefits of adding PetLabCo.® ProBright® Advanced powder to your dog’s dental care routine? The primary functions are:

• Targeting tartar build-up, especially in hard-to-reach places that a toothbrush might miss
• Helping to freshen bad breath by tackling the source of mouth odor
• Supporting clean and healthy teeth and gums 

Good to know: PetLabCo.® is National Animal Supplement Council (NASC) certified. ProBright® Advanced is third-party tested and manufactured in the USA, utilizing high-quality domestically and globally sourced ingredients.

PetLabCo.® and ProBright® Advanced Formula

PetLabCo.® has sold over 5 million products globally and is a well-known provider of science-backed, expert formulated pet supplements, including probiotics for dogs. With over 13,000 customer reviews on Trustpilot and an overall rating of ‘Great’, PetLabCo.® is widely recognized for offering a range of premium quality daily health and wellness products that fit easily into even the busiest of routines.

PetLabCo.® ProBright® Advanced is developed in collaboration with nutritionists and reviewed by veterinary dentists. The dental powder formula has been specifically designed to target tartar build-up and support fresher breath in dogs.

What sets ProBright® Advanced apart is its unique blend of ingredients, including brown algae, rosemary leaf extract, and green tea. These ingredients work together to help support fresher breath, cleaner teeth, and overall oral health. The powder is easy to use – just sprinkle one scoop of powder at mealtimes once a day as part of your dog’s dental care routine.

For pet parents seeking a reliable, science-backed way to support their dog’s dental health, PetLabCo.® ProBright® Advanced offers a convenient solution.

How PetLabCo.® ProBright® Advanced Formula Works

PetLabCo.® ProBright® Advanced is designed to target tartar build up and the accumulation of dirt on your dog’s teeth, helping support a clean mouth and fresher breath as part of a consistent dental routine.

1. Targets Tartar Build-Up on the Teeth

The formula is designed to help target tartar accumulation on your dog’s teeth, including areas that may be harder to reach with tooth brushing alone. Over time, consistent use may help support a cleaner appearance of the teeth.

2. Supports Oral Cleanliness Across the Whole Mouth

ProBright® Advanced helps maintain healthy teeth and gums, helping to support overall oral cleanliness as part of a daily dental routine. This can be especially helpful for supporting hygiene between tooth brushing sessions.

3. Helps Freshen Breath

By targeting the build-up of tartar and debris, ProBright® Advanced can help support fresher breath. This makes it a useful addition for dogs with occasional unpleasant breath.

4. Provides Ongoing Support with Daily Use

The product is designed to be used consistently once per day. Regular use can help support oral hygiene over time, rather than delivering instant results.

5. Complements a Broader Dental Care Routine

ProBright® Advanced is most beneficial when used alongside regular tooth brushing and routine veterinary check-ups. It is intended to support, not replace, other aspects of your dog’s dental care.

What Do the 2 PetLabCo.® ProBright® Advanced Clinical Studies Show?

Marketing hype aside, modern dog owners deserve the facts from clinical studies. 

1. 1. A 28-day clinical study found ProBright® Advanced significantly reduced hydrogen sulfide in a dog’s mouth, one of the most common compounds that produces bad breath, by 40%.†
2. 2. According to Dr. Jan Bellows, Board-Certified Veterinary Dentist and PetLabCo.® Consultant: “The clinical results for ProBright® Advanced demonstrate a notable advancement in at-home canine dental care. The study revealed daily use of ProBright® Advanced for 90 days resulted in a 25% decrease in plaque formation, a substantial achievement given the challenging nature of plaque control in clinical settings.”‡

As always, individual results may vary.

ProBright® Advanced vs the original ProBright® formula

Both are dental powders from PetLabCo.® with overlapping ingredients (brown algae, sodium hexametaphosphate, rosemary leaf extract). The Advanced formula adds a patent-pending probiotic blend and has been the subject of the 28-day† and 90-day‡ clinical studies referenced above. The original formula remains available as an alternative. See the original ProBright® product page for the full comparison.

How To Use PetLabCo.® ProBright® Advanced

To use PetLabCo.® ProBright® Advanced, give your dog one scoop of powder a day during mealtime, according to the provided directions.

• Choose the right size based on your dog’s weight.
• Give one scoop a day during mealtime.
• Consistency is key – daily use allows for continued tartar and breath support.

Pro Tip: I like to keep a health journal for my dog so I can log in dates, supplements added, and any changes in my pup’s overall behavior. This comes in handy for vet visits. 

As with any new product, start slowly and build up to the directed amount.

What Do Pet Parents Say?

The strongest signal that ProBright® Advanced works comes from the people using it daily. In a September 2025 survey of PetLabCo.® subscribers using ProBright® Advanced for 90+ days:

• 90% report seeing results with ProBright® Advanced*¹
• 93% report their dog’s teeth looking cleaner and healthier*²
• 82% report fresher breath in their dogs*³
• 82% notice less tartar on their dog’s teeth*⁴
• 85% recommend PetLabCo.® ProBright® Advanced to a friend*⁵

*Based on a survey of PetLabCo.® subscribers who reported using ProBright® Advanced daily or almost daily for 90+ days. Results reflect customer feedback collected in September 2025 (¹n=456; ²n=401, based on subscribers who wanted cleaner and healthier teeth; ³n=362, based on subscribers who wanted fresher breath; ⁴n=408, based on subscribers who wanted less tartar; ⁵n=443). Individual results may vary.

Direct Customer Feedback for ProBright® Advanced

Here’s a snapshot of PetLabCo.® ProBright® Advanced reviews and feedback from pet parents. All reviews can be found on the PetLabCo.® ProBright® Advanced product page or on the company’s Trustpilot page:

“I can definitely tell a difference in the appearance of my dog’s teeth. They are much brighter and there’s no visible tartar buildup.” ~ Lynn L., verified buyer

“I started using this on my dog over a year ago, and she still has absolutely no tartar on her teeth! Her vet was so impressed that she asked me how I was keeping Stella’s teeth so clean. So, of course, I bragged on your product.” ~ Sheryl S., verified buyer

“Seems to work. My youngest pup, who is now 3, has been on this faithfully for a year, and her teeth have stayed white.” ~ Sharon S, verified buyer

As a dog mom, I also use ProBright® Advanced on my Cocker Spaniel, with excellent results. The ease of use, stress-free formula, and happy dogs are three reasons pet parents report as to why they love the product. 

Long-term benefits depend on your dog’s individual response and whether ProBright® Advanced is used consistently, in conjunction with daily toothbrushing and regular veterinary dental checks. 

Who ProBright® Advanced isn’t right for

Every product has limitations, and I think honest reviews should say so. ProBright® Advanced isn’t the right fit for every pet. Consider alternatives if:

• Your dog has ongoing dental issues that need veterinary support. ProBright® Advanced supports daily oral hygiene — it isn’t a solution for existing dental health issues. See your vet for support with any dental concerns.
• You’re looking for a replacement for professional dental cleaning. ProBright® Advanced doesn’t reduce the need for regular vet dental cleanings. These are still recommended for most dogs.
• You need results within days. Many pet parents report seeing signs of support after up to 90 days of consistent daily use.
• Your dog has known chicken, iodine or algae sensitivities. The powder is designed to be low-allergen, but if your dog has known reactions to chicken, iodine or algae, consult your vet before introducing.
• You are looking for dental hygiene support for your cat. ProBright® Advanced is formulated specifically for dogs. Cat owners should look at PetLabCo.® Dental Formula, which is suitable for both dogs and cats.
• Your dog is pregnant or used for breeding purposes. Pregnant dogs or those used for breeding purposes should not use ProBright® Advanced, as safe use during pregnancy has not been determined. 
• Finally, If your dog has an overactive thyroid, consult your veterinarian prior to using this product.

Review FAQ: What Buyers Actually Want to Know

What did the ProBright® Advanced clinical studies actually measure?

There have been two clinical studies of ProBright® Advanced. The 28-day study measured hydrogen sulfide levels, one of the most common compounds responsible for bad breath, and found a 40% reduction with daily use.† The 90-day study measured plaque accumulation and found a 25% decrease in plaque formation, according to Dr. Jan Bellows, Board-Certified Veterinary Dentist.‡ Both studies used daily-use protocols matching the label instructions. Individual results may vary.

How does ProBright® Advanced compare to other dental powders on the market?

There are three main differentiators:

1. PetLabCo.®’s patent-pending probiotic blend (Pediococcus pentosaceus and Lactiplantibacillus plantarum), which supports oral health.
2. Two clinical studies with specific measured outcomes rather than general “supports oral health” claims.
3. Formulation guidance from a Board-Certified Veterinary Dentist.

Trade-offs vs competitors: ProBright® Advanced can be slightly more expensive per tub than some budget options, but the monthly subscription offers a substantial saving.

What are the most common considerations in customer reviews?

Reviewing thousands of customer feedback entries on PetLabCo.® and Trustpilot, some owners expect visible tartar reduction in weeks, but the clinical evidence supports 28-90 days for measurable results.†‡ A smaller subset of dogs require an initial adjustment period to get used to the chicken-liver flavour and powder texture. A handful of reviews mention initial digestive adjustment when starting. Overall satisfaction remains high – 85% of surveyed subscribers recommend ProBright® Advanced to a friend.*⁵

Is ProBright® Advanced worth the subscription cost?

At $28.95/month for the Extra Small size (subscription with 20% discount + free shipping), it’s competitively priced against comparable clinically-tested dog dental powders – most of which cost $30-45 per tub without shipping. Considering the reported signs of support from thousands of pet parents, ProBright® Advanced can be a valuable part of an at-home routine that supports oral hygiene between vet visits.

Final verdict: Is ProBright® Advanced Worth Trying?

Overall rating: 4.5/5

Verdict: Yes, ProBright® Advanced works well as a supportive addition to your dog’s dental routine – it is best for dogs with mild tartar whose owners struggle with daily brushing.

Why I recommend it:

• Two clinical studies with specific measured outcomes (40% reduction in a bad-breath-causing compound in 28 days†; 25% decrease in plaque formation in 90 days‡)
• Strong customer feedback — 90% of surveyed subscribers report seeing results*¹
• Formulated with a Board-Certified Veterinary Dentist
• NASC-certified and third-party tested

Why you might skip it:

• Not right for existing dental issues (see a vet)
• Not a replacement for professional cleaning
• Requires patience – many pet parents report signs of support at month 2-3
• Not suitable for cats

Buy it if: You want simple, low-effort daily dental support with clinical evidence behind it.

Skip it if: You want overnight results, or your dog has existing dental care concerns.

See PetLabCo.® ProBright® Advanced product page for more information, or to purchase this product.

This product is a health supplement. If your dog has existing dental concerns or sensitivities, consult your veterinarian before use.

---

Related Products

---

Recommended Reading